Wave Audio's CR8 is an one shot sampler based plugin with the ability to create key groups, layers, multi-samples, time stretch, & granulize wav files. It works in both Windows & MacOSX (and in all DAWS). It comes with an A.I. driven sample manager that replaces sounds based on transient characters & "smart tag" it. The stand out feature of CR8 is the ability to modulate parameters. Let me know how you feel about this in the comments!